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PAIR in Hepatic Hydatidosis: Aspiration versus Albendazole in Hepatic Hydatidosis.

Khuroo MS, Dar MY, Yattoo GN, Zargar SA, Javaid G, Khan BA, Boda MI. Percutaneous drainage versus albendazole therapy in hepatic hydatidosis: a prospective, randomized study. Gastroenterology. 1993 May;104(5):1452-9. doi: 10.1016/0016-5085(93)90355-g. PMID: 8482455.

Based on the results of this randomized trial it was concluded that i. percutaneous drainage of hydatid cysts in the liver is safe and affective; ii. albendazole therapy alone is unpredictable in treating hydatid cysts of liver and iii. concommitant albendazole therapy with percutaneous drainage has potential advantages and is reasobaly safe. Now all patients undergoing PAIR technique for hepatic hydatid cysts receive prior 10 days albendazole 10mg/kg body weight per day and albendazole 400 mg orally 4 hours prior to procedure. 

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